Patent pending · U.S. Provisional Application E · Composition-of-matter licensing

Discovery Licensing

BivectorAI's geometric screening platform has identified drug and material candidates included in BivectorAI U.S. Provisional Application E (No. 64/150,473, filed September 8, 2026). The candidate records are included within the bounded composition-of-matter scope of Application E. All candidates below are computational research outputs. No compound has undergone wet-lab synthesis, experimental validation, or clinical testing. Use in drug or material development requires independent experimental validation, regulatory approval, and compliance with applicable law.

This is not a self-service product. Access requires an NDA and a direct engagement — Commercial terms are discussed privately and confirmed by written agreement.

Bounded discovery catalog

Two computational candidate portfolios. One direct licensing path.

Review the currently published candidate sets, their explicit computational evidence boundary and the commercial structure for direct evaluation under NDA. This page is a licensing catalog, not a self-service discovery engine.

325 Drug candidates

325 filed candidate records · 323 unique molecular species · 52 target series · 17 registry disease-area labels.

439 Material candidates

439 unique computational material candidates · 197 P1 + 242 P2 · 200 with Materials Project negative-search evidence.

Application E · Drug Candidate Compositions

325 candidates across 52 target series

118 distinct structural scaffold clusters. 323 unique exact molecular species. Screened computationally across target-engagement, selectivity, safety-signal and synthetic-accessibility evidence dimensions.

Therapeutic areas represented in the filed candidate set

Application E contains 325 drug-candidate records across 52 target series and 17 registry disease-area labels. The portfolio is presented publicly by therapeutic relevance so pharmaceutical and biotechnology teams can identify applicable programs without exposing candidate structures.

The headings below are customer-facing groupings of target coverage disclosed in Application E. They are not presented as a verbatim list of the filing's 17 internal disease-area labels.

Oncology & cancer research

Candidate series relevant to targeted oncology, kinase signaling, mutant oncogenes and DNA-damage-response programs.

Filed target coverage includes MET, ABL, ALK, BRAF, HER2, CDK2, CDK4, CDK6, ATR, PARP1, BTK, FLT3, IDH1, IDH2, JAK2, KRAS G12C, KRAS G12D, AKT1, mTOR, PI3Kα, FGFR1, RET and VEGFR2.

Cardiovascular, coagulation & lipid research

Candidate series relevant to cardiovascular, coagulation, thrombosis and lipid-pathway programs.

Filed target coverage includes ACE, Factor Xa, HMG-CoA reductase, PCSK9 and Thrombin.

CNS & neurodegeneration research

Candidate series relevant to neurological and neurodegeneration drug-discovery programs.

Filed target coverage includes AChE, GSK3β, MAO-B and BACE1.

Infectious-disease research

Candidate series span viral, parasitic and bacterial target programs.

Filed target coverage includes SARS-CoV-2 Mpro and PLpro, HIV integrase, HIV protease, HIV reverse transcriptase, PfDHFR, PfDHOD, InhA and TB-INHA-R.

Inflammation & immune-pathway research

Candidate series relevant to inflammatory and immune-signaling drug-discovery programs.

Filed target coverage includes COX-2, JAK1, PDE4B and TACE/ADAM17.

Metabolic & diabetes-related research

Candidate series relevant to metabolic and diabetes-related drug-discovery programs.

Filed target coverage includes aldose reductase, DPP-4 and PPARγ.

Cardiac function & rhythm research

Candidate series relevant to cardiac signaling, calcium handling and rhythm-focused research.

Filed target coverage includes CaMKII, PKCα and RyR2.

Antifungal research

A dedicated fungal target program is represented in the filed candidate registry.

Filed target coverage includes CYP51.

How far the drug candidates have progressed

These are candidate-level computational records, not merely target ideas. Application E reproduces exact molecular identities and associated screening evidence, while physical and clinical validation remain future gates.

325 filed drug-candidate records
323 unique molecular species after canonicalization
118 structural scaffold clusters
52 target-specific series
Completed · Identity Exact candidate identities established

All 325 source records have complete molecular identity in Application E. Exact structures remain off the public website.

Completed · Screening Computational evidence recorded

Filed records include target screening, computational safety and drug-likeness, synthetic-accessibility and docking-related evidence.

Completed · Database search PubChem search evidence available

The September 1, 2026 search recorded 255 source records with no PubChem match and 70 with PubChem matches.

Next gate · Experimental Wet-lab and clinical work remains

Application E does not represent these candidates as synthesized, experimentally validated, clinically validated or approved.

294 records with QED ≥ 0.5
319 records with positive docking-pose count
256 records carrying registry eligibility
237 registry eligible + QED ≥ 0.5 + positive docking
Public: therapeutic area, representative target coverage, portfolio scale and aggregate evidence stage. Protected for NDA review: exact structures, candidate identifiers, candidate-specific results, structural records and proprietary discovery methodology. PubChem no-match status is database-search evidence, not a final legal novelty determination.
Small series (1–5 candidate records) · 11 series, 41 candidate records
On request option
Upfront payment, milestones and royalties negotiated
Medium series (6–12 candidate records) · 38 series, 230 candidate records
On request option
Upfront payment, milestones and royalties negotiated
Large series (13–24 candidate records) · 3 series, 54 candidate records
MET, IDH1+PCSK9+PDE4B, BRAF+INHA+TBINHAR
On request option
Upfront payment, milestones and royalties negotiated
Complete drug portfolio — exclusive worldwide, all 52 series / 325 candidate records (323 unique molecular species)
On request option and exercise terms
Milestone framework on request · Royalty negotiated

Request Evaluation →

Application E · Material Candidate Compositions

439 computational exact-formula candidates

The 439 computational material candidates are maintained with supporting and negative-evidence records for bounded evaluation. Detailed prioritization methodology and source-specific screening records are reserved for qualified review under NDA.

Material application areas represented in Application E

Application E contains 439 unique computational material-candidate formulas: 197 P1 and 242 P2. The filing also contains structural and application support across 17 material template families. Exact candidate formulas are not published here.

The categories below describe application relevance supported by material families reproduced in Application E. They are not a claim that all 439 candidates are evenly distributed among these categories.

Batteries & solid electrolytes

Filed family support includes solid-electrolyte, sodium electrochemical and battery-coating contexts.

Relevant to battery manufacturers, solid-state battery developers and advanced energy-storage R&D.

Semiconductors & 2D materials

Filed support includes nitride, 2D semiconductor and thin-film material families.

Relevant to semiconductor, electronics and advanced-device R&D.

Memristive & electronic materials

Application E includes memristive-oxide structural and application support.

Relevant to advanced memory, switching and electronic-material research.

Porous materials & MOFs

Filed framework support includes gas capture, storage, separation and water-interaction applications.

Relevant to carbon-management, industrial-gas and separation technology.

Catalysis

Application E includes nitrogen-fixation and CO₂-reduction catalyst family support.

Relevant to chemical manufacturing, carbon conversion and catalytic-process R&D.

Superconducting materials

Nickelate-superconductor material families are represented in the filed application.

Relevant to superconductivity and condensed-matter research.

Thermoelectric materials

Filed support includes skutterudite and Half-Heusler material families.

Relevant to thermal-energy conversion and waste-heat recovery.

Magnetocaloric materials

Magnetocaloric structural/application support is reproduced in Application E.

Relevant to advanced thermal-management and solid-state cooling research.

Piezoelectric materials

Piezoelectric material families are represented in the filed structural support.

Relevant to sensing, actuation, transduction and energy harvesting.

High-entropy structural alloys

Application E includes high-entropy structural-alloy family support.

Relevant to advanced structural and high-performance engineering materials.

Ultra-high-temperature ceramics

Ultra-high-temperature ceramic families are represented in Application E.

Relevant to extreme-temperature and aerospace-material research.

Antimicrobial coatings

Antimicrobial-coating material families are included in the filed support.

Relevant to functional coatings, surfaces and antimicrobial-material research.

How far the material candidates have progressed

The filed portfolio has progressed to exact formula-level candidate identity, P1/P2 prioritization and database-search evidence. Experimental material properties remain a future validation gate.

439 unique computational candidate formulas
197 P1-priority records
242 P2-priority records
200 Materials-Project-negative search records
Completed · Identity Exact formula-level identities filed

Application E reproduces all 439 computational candidate formulas. Exact formulas remain off the public website.

Completed · Priority 197 P1 + 242 P2

Every candidate in the current 439-record set carries a P1 or P2 priority classification.

Completed · Database search Materials Project evidence recorded

19 records were element-system negative and 181 additional P1 records were exact-formula negative, producing 200 database-negative records.

Next gate · Experimental Physical validation remains

Experimental synthesis, phase confirmation, property measurement and application qualification are not represented as completed.

Source records state CIF availability for all 439 candidates. Application E does not reproduce the atomic coordinates, lattice parameters or space groups, so the filed support remains bounded at formula and supported-family level rather than a public claim of experimentally verified crystal structures or polymorphs.
Public: material application area, portfolio scale, priority class and aggregate validation stage. Protected for NDA review: exact formulas, candidate identifiers, candidate-specific crystal records, detailed scores and proprietary discovery methodology. Materials Project no-match status is database-search evidence, not a final legal novelty determination.
Complete material portfolio — exclusive worldwide, all 439 computational formulas
On request option and exercise terms
Milestone framework on request · Royalty negotiated

Request Evaluation →

Scope note

Pricing above covers only the drug and material candidate compositions included in U.S. Provisional Application E (No. 64/150,473). It does not include additional candidate sets that are not included in that filed application.